In the ever-changing milieu of living organisms, maintaining optimal health relies on the delicate balance of homeostasis. Disruptions in this intricate environment can give rise to various diseases. Embracing the theme 'One Endo' at SICEM 2024, this session brings together emerging scientists to share cutting-edge research in human endocrinology and metabolism. Speakers will focus on mechanisms related to homeostasis, presenting research on energy metabolism, glucose homeostasis, and feeding behaviors. Join us for insightful discussions and explore the evolving frontiers of human endocrinology research.

This session explores cutting-edge research, elucidating the fundamental mechanisms behind metabolic regulation and cellular identity. Three distinguished speakers will share their insights on recent research, new developments in our understanding of liver metabolic disease, the epigenomic control involved in macrophage specialization, and the intricate mechanisms shaping cellular diversity in adipose tissue.

The hypothalamus and brainstem intricately regulate physiological functions, including appetite and body weight, influencing the delicate balance between hunger and satiety. Prof. Amber L. Alhadeff will introduce distinct GLP-1 receptor circuits regulating satiety and aversion. Next, Prof. Lisa Beutler will share recent findings on obesity-mediated dysregulation of the gut-brain axis. Finally, Prof. Chan Hee Lee will present the role of hypothalamic microgliosis in cancer-associated cachexia.